Recent Activity
Panzica Updated Gene Info
Panzica Updated Alias
Naomi Updated Alias
Recent Papers
Wu P, Mo W, Tian T, Song K, Lyu Y, Ren H, Zhou J, Yu Y, Lu H (2024) Transfer of disulfide bond formation modules via yeast artificial chromosomes promotes the expression of heterologous proteins in . mLife 3:129-142

Kong W, Ding G, Cheng G, Yang P, Xu Z (2024) Mucosal immune responses to in the ocular mucosa of rainbow trout (, Walbaum), an ancient teleost fish. Marine life science & technology 6:266-279

Hao H, Lian Y, Ren C, Yang S, Zhao M, Bo T, Xu J, Wang W (2024) RebL1 is required for macronuclear structure stability and gametogenesis in . Marine life science & technology 6:183-197

What's New

Tetrahymena Genome Data files

Posted on 2023-09-18 12:54:11 by ciliate-curator

We have revamped the arrangement of files under the Genome Data tab found under the Resources menu on TGD. The last annotation of the Tetrahymena thermophila genome was published in 2020, and was the fifth version of genome files to be released to the community. We have labeled these "v5" in the file handles, to help denote them as the latest genome files, and to distinguish them from previous and future versions. The other three Tetrahymena species hosted at TGD (elliotti, borealis, and malaccensis) were only sequenced and annotated once to date, and are labeled "v1". All other files available at the site are listed by date under "Legacy Files". If you have any questions, please contact us at

2023 Ciliate Molecular Biology Meeting

Posted on 2023-04-03 21:43:54 by ciliate-curator

The 2023 Ciliate Molecular Biology Meeting will be held from June 26 to 29, 2023 in Montpellier, France. The early registration and abstract submission deadline is April 15, with late registration extending until May 15.

For questions related to the registration and requesting a letter for your visa application, please send an e-mail to

For more details, please visit the meeting website at:

Website updates; new genome browser and BLAST interface

Posted on 2022-11-17 14:45:17 by ciliate-curator

Tetrahymena Genome Database Wiki is currently undergoing scheduled website updates. We have replaced the GBrowse genome browser with JBrowse2 and are using this GMOD software to display the T. thermophila macronuclear and micronuclear genome sequences. We have also created a new BLAST server interface. Several community database edits from the last year will be added back before December 1. The T. malaccensis, T. elliotti, and T. borealis genomes will be displayed in JBrowse2 in the next month.

OxyDB has been updated!

Posted on 2021-10-29 00:24:36 by ciliate-curator

We have made changes to OxyDB to reflect the latest reannotation of the genome. Gene names displayed on OxyDB pages have been changed and now link to the updated genome browser. The previous annotation can still be searched using the BLAST server and legacy GBrowse genome browser.

Special Issue of Microorganisms (ISSN 2076-2607): Ciliates as Model Organisms: From ‘omics’ to Genetics, Ecology and Signaling

Posted on 2021-03-22 00:00:00 by ciliate-curator

This Special Issue is open to reporting all studies on ciliates as model organisms, seeking to understand their genetics, cell biology, biochemistry, evolution, ecological adaptation, and the complex mechanisms of signaling systems, from the genes involved to the changes in gene expression during cell response, and from the structure and involved evolution of signal molecules to the membrane traffic in the cells. The deadline for submission is 31 December 2021. We look forward to receiving your contributions. Prof. Dr. Cristina Miceli Prof. Dr. Adriana Vallesi Guest Editors Dr. Ronald Edward Pearlman Co-Guest Editor

Interactions Methods Paper Published

Posted on 2021-03-22 00:00:00 by ciliate-curator

A new paper on methods to identify protein interactions in Tetrahymena has been published. Functional proteomics protocol for the identification of interaction partners in Tetrahymena thermophila. Congratulations to the authors!

Tetrahymena thermophila macronuclear genome fully completed

Posted on 2020-04-16 00:00:00 by ciliate-curator

We have received an update of the Tetrahymena thermophila genome sequence from researchers at Ocean University of China. The gene pages, BLAST server, and Genome Browser have all been updated accordingly to display these new data. Congratulations to the team involved in this effort!

A publication explaining the new sequences and features has been published:
The completed macronuclear genome of a model ciliate Tetrahymena thermophila and its application in genome scrambling and copy number analyses.
Sheng Y, Duan L, Cheng T, Qiao Y, Stover NA, Gao S.
Sci China Life Sci. 2020;10.1007/s11427-020-1689-4. doi:10.1007/s11427-020-1689-4

Proteomics Review Published

Posted on 2019-05-01 00:00:00 by ciliate-curator

A review of nuclear proteomics results described for Tetrahymena thermophila by Saettone, et al. has been published in the journal Genes. Congratulations to the authors!